MethCP: Differentially Methylated Region Detection with Change Point Models (bioRxiv)

1 MethCP: Differentially Methylated Region Detection with Change Point Models

Boying Gong, Elizabeth Purdom, MethCP: Differentially Methylated Region Detection with Change Point Models, 2018, bioRxiv.

https://doi.org/10.1101/265116 Permanent link to the paper]

1.1 Summary

A new approach (MethCP) for the identification of differentially methylated regions (DMRS) of the DNA based on whole genome sequencing data is supposed. The approach is develope for more complex design than two-group comparisons, e.g. for time course experiments. For the two-group setup, it is claimed that MethCP outperforms existing approaches.

1.2 Study outcomes

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1.2.1 Outcome O1

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1.2.2 Outcome O2

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1.2.3 Outcome On

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1.2.4 Further outcomes

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1.3 Study design and evidence level

1.3.1 General aspects

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1.3.2 Design for Outcome O1

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1.3.3 Design for Outcome O2

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1.3.4 Design for Outcome O

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1.5 References

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